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  • The Role of Synthetic DNA in Big DNA and Genetics Research

    Friday, August 02, 2013
    Technical Article
    Dan Gibson Hans Packer
    Synthetic biology is defined as the de novo design and construction of biological devices and systems, and as such is heavily reliant on the use of synthetic DNA. The size and sequence of potential ... read more

  • A Capillary Gel Electrophoresis Fluorescence System for Antibody–Antigen Interactions

    Wednesday, August 07, 2013
    Application Note
    Shou-Kuan Tsai Ming-Jhy Hseu Varoujan D. Amirkhanian
    Since its inception more than 20 years ago, slab gel-based electrophoresis technology has been used routinely for the analysis of biomolecules (i.e., DNA, proteins, and carbohydrates). However, use of... read more

  • DNA in Forensics

    Wednesday, August 28, 2013
    Technical Article
    Robert L. Stevenson, Ph.D.
    The proliferation of forensic DNA testing and databases by state and local jurisdictions was recently reported by Joseph Goldstein in The New York Times. For years, the FBI’s combined indexing system ... read more

  • New Products for Gas Chromatography at Pittcon® 2014

    Tuesday, May 06, 2014
    Application Note
    Robert L. Stevenson, Ph.D.
    Pittcon® is changing rapidly. After decades where separation science including GC/MS and LC/MS dominated the meeting, a report by Dr. Matt Wilkinson in this issue demonstrates that optical ... read more

  • Next-Generation Sequencing for Disease Biomarkers

    Monday, December 15, 2014
    Application Note
    Darren Lee
    Next-generation sequencing (NGS) is beginning to provide powerful insights into genetic mutations and molecular networks underlying disease for a broad set of genes. NGS technologies promise to ... read more

  • Reference Standards Address Technical Challenges in DNA Resequencing

    Tuesday, August 04, 2015
    Application Note
    Natalie A. LaFranzo
    The extensive workflow required to analyze DNA samples using next-generation sequencing (NGS) leaves many opportunities for the introduction of variability. read more

  • Long Reads and the Return of Reference Genomes

    Thursday, February 18, 2016
    Application Note
    Chris Boles Jonas Korlach
    The availability of inexpensive, massively parallel short-read sequencers shifted the focus of high-quality reference genome production to resequencing and draft genome assemblies, emphasizing ... read more

  • Long-Range Sequencing is Required to Unlock the Full Genome

    Friday, February 19, 2016
    Application Note
    Michael Schnall-Levin
    Next-generation sequencing (NGS) provides unprecedented access to one of biology’s greatest mysteries—the genome. read more

  • The Future of DNA Synthesis

    Thursday, May 26, 2016
    Application Note
    Devin Leake
    Since the launch of the Human Genome Project, the genomes of over 180 organisms have been sequenced. read more
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